Hamilton Microlab 600 and 700 Diluters, Dispensers and Syringe Pumps

Hamilton Microlab 600 and Microlab 700 are semi-automated benchtop liquid handlers built on positive displacement syringe pumps. They are configured as dual-syringe diluters, single- or dual-syringe dispensers and continuous dispensers, and they handle the tasks that are too small to automate and too large to do reliably by hand. The positive displacement system provides better than 99% accuracy, independent of the viscosity, vapor pressure and temperature of the liquid, and the inert fluid path (borosilicate, PTFE and CTFE) minimizes sample carryover. Mikron Proses (Üsküdar, Istanbul) is one of Hamilton’s distributors in Turkey and provides application consulting on model selection, syringes and accessories.

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Microlab 600 and 700 compared

	Microlab 600	Microlab 700
Controller levels	Basic, Advanced	Advanced, Premium
Screen	5.7 inch touchscreen (640 × 480)	7 inch touchscreen (1280 × 800)
Models	3 diluter models, 6 dispenser models	3 diluter models, 6 dispenser models
Accuracy / precision	±1% / ±0.2%	±1% / ±0.2%
Single-step dilution	Up to 1:50,000	Up to 1:50,000
Dispense volume	500 nL to 50 mL	Up to 50 mL (see note)
Syringes	10 µL to 50 mL; Bubble Free Prime and SaltLine	10 µL to 50 mL; Bubble Free Prime and SaltLine
Software	Basic: Quick Start screen for standard dilutions and dispensing. Advanced: methods with air gaps, washing and repetitive dispensing, Wizards, Favorites, custom methods, more than 1,000 methods, log files, 10 languages	Wizards (including Dry Weight Dilution with a connected balance), Favorites, custom methods, audit trail viewer, maintenance reminders, GMP/GLP printer menu, 6 languages
21 CFR Part 11 and GMP/GLP	Advanced: security options and LyncStore log management	Security settings (multiple administrators, PDF signatures, automatic sign-out); LyncStore 700 and REST-API only in Premium
Connectivity	Ethernet 10/100	Ethernet, Wi-Fi, USB; Premium: REST-API for LIMS and mobile devices
Calibration and certification	N.I.S.T. traceable; CE, CSA	N.I.S.T. traceable; CE
Upgrade	Basic to Advanced with a software kit (P/N 61500-02)	Advanced to Premium with an activation key (P/N 10101502)

Note: the Microlab 700 brochure gives the dispense volume range as 100 nL to 50 mL in its text and as 1.0 µL to 50 mL in its specification table, so no lower limit is stated here. Sources: Microlab 600 Catalog Rev J and Microlab 700 Brochure 10108577.

Diluter models

A dual-syringe diluter takes the sample with the small syringe and the diluent with the large syringe, and makes a high-ratio dilution in a single step. The diluent washes the line between samples, which minimizes carryover in sensitive techniques such as AA, ICP, HPLC and GC.

Model	Series	Controller	Hand probe
ML615-DIL	600	Basic	Concorde
ML625-DIL	600	Advanced	Concorde
ML625-DTHP	600	Advanced	Disposable Tip Hand Probe (DTHP)
ML715-DIL (10103468)	700	Advanced	Concorde
ML725-DIL (10103471)	700	Premium	Concorde
ML725-DTHP (10103470)	700	Premium	Disposable Tip Hand Probe (DTHP)

With the Disposable Tip Hand Probe, the sample is drawn into a disposable ClickSure tip (50 µL and 1 mL, 960 tips per rack or bulk), which eliminates carryover.

Dispenser models

There are three configurations: a single-syringe dispenser, a dual-syringe dispenser and a continuous dispenser, in which one syringe fills while the other dispenses so that the instrument is always ready. Built-in Wizards cover aliquot dispensing, serial dispensing, titration and pipetting.

Model	Series	Configuration	Controller
ML610-DIS	600	Single syringe	Basic
ML615-DIS	600	Dual syringe	Basic
ML615-CNT	600	Continuous	Basic
ML620-DIS	600	Single syringe	Advanced
ML625-DIS	600	Dual syringe	Advanced
ML625-CNT	600	Continuous	Advanced
ML710-DIS (10103458)	700	Single syringe	Advanced
ML715-DIS (10103461)	700	Dual syringe	Advanced
ML715-CNT (10103465)	700	Continuous	Advanced
ML720-DIS (10103460)	700	Single syringe	Premium
ML725-DIS (10103464)	700	Dual syringe	Premium
ML725-CNT (10103467)	700	Continuous	Premium

If no syringes are selected when ordering, the -DIS models ship with 1 mL syringes and, in the Microlab 700 brochure, the -CNT models with 10 mL syringes; diluters ship with 2.5 mL and 250 µL syringes.

Standalone syringe pumps

The ML630 (single syringe) and ML635 (dual syringe) are controlled from an external system and are listed with the same codes in the Microlab 600 catalog and the Microlab 700 brochure. If no syringe is selected, they ship with 1 mL syringes.

• Ethernet gives access to the full details of the pump and remote control; it is programmed through the .NET 2.0 application programming interface, for example from Visual C#, Visual Basic or LabVIEW. It suits remote dispensing in restricted environments.
• RS-232 is the choice if the control device is a programmable logic controller, if a platform other than Windows with .NET 2.0 is used, or if an older RS-232 device such as the Microlab 500 or a Modular Valve Positioner is involved.

For analytical syringes and needles, see Hamilton precision syringes, needles and chromatography accessories.